SEPN
Septerna, Inc. Common StockNASDAQ
Healthcare • Biotechnology
Updated 1 day ago
Coverage limited
Factor tilt: Momentum-tilted Small Cap
$36.42-3.05%
Close Oct 13, 2026
- Market cap
- $1.64B
- 1 month
- -7.9%
- 3 months
- +6.9%
- 1 year
- +57.8%
- 52-week range
- $18.10$48.19
- Dividend
- No dividends on record
- Next-quarter EPS estimate
- -$0.40Quarter to Sep 30, 2026 · 4 analysts · revenue $20.78M
- Short interest
- 11.7% of float3.1M shares · settled Sep 30, 2026 · +7.0% since Sep 15, 2026 · FINRA
Fundamentals · trailing 12 months to Jun 30, 2026
- Revenue
- $98.88M
- Net income
- -$24.24M
- Free cash flow
- $105.1M
- Book value
- $386.72M
- Total debt
- $22.55M
- P/E
- —
- Price / sales
- 16.6×
- Price / book
- 4.2×
- FCF yield
- +6.4%
- Net margin
- -24.5%
EODHD (TTM) · as of Oct 13, 2026
End-of-day close from stored market data, not a live quote.
Portfolio context
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Loading market dates
No upcoming ex-dividend date announced
No 8-K filings in the last 30 days.
Smart money context
Holder IQ: HIGH
32 top institutions tracked
as of 2026-Q2 (filed 2026-09-22)
Last 13F trend: unchanged (light)
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Sentiment: bearish
Last trade: sell 41 days ago
Red flags: 0
Largest 13-F holders · Q2 2026
154 filers reported a long position in SEPN for Q2 2026. 13-F holdings are filed up to 45 days after the quarter ends.
| Holder | Value | Shares | Shares vs Q1 2026 |
|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | $234.3M | 7M | Unchanged |
| TRV GP V, LLC | $208.2M | 6.2M | Unchanged |
| DRIEHAUS CAPITAL MANAGEMENT LLC | $148.5M | 4.4M | +0.9% |
| TRV GP VI, LLC | $141M | 4.2M | Unchanged |
| Samsara BioCapital, LLC | $105.5M | 3.1M | Unchanged |
| GOLDMAN SACHS GROUP INC | $102.6M | 3.1M | +5.4% |
| BlackRock, Inc. | $64.7M | 1.9M | +6% |
| Siren, L.L.C. | $63.6M | 1.9M | -5% |
| Avoro Capital Advisors LLC | $44.8M | 1.3M | Unchanged |
| Jupiter Topco LLC | $43.7M | 1.3M | — |
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